Streptokinase Infusion Calculator

Before starting streptokinase, check coagulation, fibrinogen level and platelet count and discuss with consultant in charge

Wt of infant (kg)
Dose (range 1000-6000 units/kg/hour)
Flow rate (ml/hr)
Volume of infusion to be made up (ml)

First reconstitute 250,000 unit vial in 5 ml water for injection. This solution contains 50,000 units streptokinase/1 ml

Diluent: 5% or 10% glucose or 0.9% sodium chloride

Amount of streptokinase to add to diluent (units)

Volume of streptokinase injection (50,000 units/1ml) to add to diluent (ml)

Volume of diluent (ml)